Tox-Train Getting USEtox out of the lab

TOX-TRAIN stands for the implementation of a toxicity assessment tool for practical evaluation of life-cycle Impacts of technologies. The four-year long project aims at creating a user-friendly toolbox to assess toxicological impacts related to the life-cycle of technologies. The partners of TOX-TRAIN, experts of both commercial and academic organizations are to transform the latest scientific developments into a usable and efficient product for researchers, industries and everyone interested in toxic life-cycle impact assessment of technologies.

Download the TOX-TRAIN leaflet or poster.

Project objectives

  • Improve toxicity impact assessment models
  • Quantify chemical emissions and potential impacts
  • Apply developments in case studies
  • Put forward an update proposal for USEtox®
  • Provide training and outreach of USEtox®
  • Document and provide guidelines of the developments

The validity, applicability and relevance of toxic impact assessment in the life cycle of products will be tested and improved for a selected number of chemicals, focusing on the USEtox® model. The substance coverage of USEtox® will be expanded, new emission quantification models will be developed, indoor exposure models for work place and household will be included and finally the outcomes will be tested in case studies.

The project runs from 2011 to 2015 and is part of the seventh framework programme under the Industry-Academia Partnerships and Pathways (IAPP) of the Marie Curie actions with the grant agreement number 285286. Visit the project's page on the EU Community Research and Development Information Service.

About USEtox

This video was co-sponsored by the TOX-TRAIN project

USEtox® was built as a scientific consensus model for toxic impacts considering a balance between state-of-the-art science and the need for stability and reliability on the level of application.

Recommended by the United Nations Environment Programme and the European Commission, used by the US Environmental Protection Agency and other organizations, USEtox® is increasingly used for application in comparative toxicity assessment and various LCA tasks such as hot spot identification, comparison of alternatives or labelling.

Check the new www.usetox.org website

Questions about USEtox? Check their extensive FAQ section and User Forum.

The partners

Coordination and scientific developments

Quantification of chemical emissions
Coupling of chemical emission and impact quantification modeling
Indoor exposure in household and occupational setting
Test new models in case studies

Contact

Technical University of Denmark
Division for Quantitative Sustainability Assessment (QSA)
Attn: Peter Fantke
Produktionstorvet, Building 426
2800 Kgs. Lyngby, Denmark
Tel: +45 45254452
Email: pefan@dtu.dk
Visit website

Model enhancements and uncertainties

Degradation, partitioning and toxicity estimation for emerging compounds
Parameter uncertainty calculation of estimation routines
Indoor exposure in household and occupational setting
Test new regression models in case studies

Contact

Radboud University Nijmegen
Dpt of Environmental Science
Attn: Rosalie van Zelm
P.O. Box 9010
6500 GL Nijmegen, The Netherlands
Tel: +31 243652923
Email: R.vanZelm@science.ru.nl
Visit website

Data providing and testing

Data provision on chemical emissions
Supply industrial case scenarios to calibrate models
Provide case studies for application
Industry advice on developments

Contact

Veolia Environnement
Recherche et Innovation (VERI)
Attn: Sandrine Sourisseau
Centre de Recherche de Rueil-Malmaison
10 rue Jacques Daguerre
92500 Rueil-Malmaison, France
Tel: +33 2 43 65 29 23
Email: sandrine.sourisseau@veolia.com
Visit website

Communications and dissemination

Collecting feedback from USEtox users
Creating a user-friendly tool and interface for USEtox
Providing documentation and user guidelines
Organizing training sessions

Contact

Quantis
Attn: Xavier Bengoa
EPFL Innovation park, Bâtiment D
1015 Lausanne, Switzerland
Tel: +41 21 693 91 98
Email: xavier.bengoa@quantis-intl.com
Visit website

Questions about TOX-TRAIN? Contact toxtrain@quantis-intl.com.

Courses

  • 12 May 2013: SETAC EU 2013 - USEtox scientific short course (Glasgow, UK)
  • 25 August 2013: LCM 2013 - USEtox application in life cycle assessment (Gothenburg, Sweden)
  • 25 September 2013: ILCM 2013 - USEtox scientific short course (Bangalore, India)
  • 30 September 2013: LCA XIII - Practical course on USEtox and life cycle assessment (Orlando, FL, USA)
  • 6 May 2014: USEtox application in life cycle assessment (Nijmegen, The Netherlands)
  • 11 May 2014: SETAC EU 2014 - USEtox scientific short course (Basel, Switzerland)
  • 14 September 2014: SETAC Asia Pacific/SETAC Australasia Conference 2014 - USEtox scientific short course (Adelaide, Australia)
  • 3 May 2015: SETAC EU 2015 - USEtox scientific short course (Barcelona, Spain)
  • 30 August 2015: LCM 2015 - USEtox 2.0 application in life cycle assessment (Bordeaux, France)

Workshops

- Workshop on pesticides modelling in life cycle assessment (round 1) (2013) -

This workshop attempts to establish broad consensus about the delimitation between the life cycle emission inventory and impact assessment for agricultural applications of pesticides in life cycle assessment (LCA). The workshop is organised back to back with the SETAC EU meeting in Glasgow, UK.

When: Saturday 11 May 2013, 8:00 – 19:00

Where: Glasgow, UK

Who: Over 30 experts from all continents working with/on LCA (application or method development), or representing pesticides producers, users, or regulators

Organisers: The Technical University of Denmark and Quantis with the support of the EU project TOX-TRAIN and the USEtox team

Objective: Create consensus about clear guidelines for LCA practitioners, data (base) and characterisation method developers, and decision makers where the boundary between the product system model (emission inventory) and the environmental model (impact assessment) should be set in all three spatial dimensions. The workshop is not about how to quantify emissions or related impacts of pesticides and fertilizers, but focusing on clearly defining what should be quantified in the emission inventory of the product system and what should be quantified by the characterisation factors from the impact characterisation models, avoiding any overlap or double counting of processes.

Download the workshop description

Access the paper which resulted from the workshop: Rosenbaum et al. (2015).

- Workshop on pesticides modelling in life cycle assessment (round 2) (2014) -

This workshop attempts to establish broad consensus about how to consistently model in LCA the fractions of applied pesticides that enter air, water, soil, and agricultural crops as emissions. The workshop is organised back to back with the SETAC EU meeting in Basel, Switzerland.

When: Saturday 10 May 2014, 8:00-18:00

Where: Basel, Switzerland

Who: Experts working with/on LCA (application or method development), or representing pesticides producers, users, or regulators

Organisers: The Technical University of Denmark, Dr. Knoell Consult GmbH and Quantis with the support of the EU project TOX-TRAIN

Objective: To establish recommended default “emission fractions to environmental media via initial pesticide distribution”. More specifically, to discuss how to consistently model in life cycle assessment (LCA) the fractions of applied pesticides that enter air, water, soil, and agricultural crops as emissions. We will thereby target the feasibility to implement these applied pesticide fractions along with associated data requirements into current LCA emission software.

Download the workshop description

- Workshop on pesticides modelling in life cycle assessment (round 3) (2015) -

This workshop attempts to finalize the consensus building process on how to model in LCA the fractions of applied pesticides that enter air, water, soil, and agricultural crops as emissions. The workshop is organised back to back with the LCM 2015 Conference in Bordeaux, France.

When: Saturday 29 August 2014, 8:00-18:00

Where: Bordeaux, France

Who: Experts working with/on LCA (application or method development), or representing pesticides producers, users, or regulators

Organisers: The Technical University of Denmark, IRSTEA and Quantis with the support of the EU project TOX-TRAIN

Objective: Building on the Scoping Workshop in May 2013 in Glasgow (UK), the Technical Framework Workshop in May 2014 in Basel (CH), and Follow-up Task Force work, we will now strive toward consensus in proposing default pesticide emission fractions for use in LCA.

Download the workshop description

Case studies

Several case studies were deployed in the project's Work Package #4 to demonstrate the validity and applicability of new outcomes from other work packages. Environmental data for the sector of environmental services will be collected to calculate new characterization factors for priority substances. The following studies will be conducted:

1. Environmental performance of waste water treatment plants (WWTP)

  • Removal of micro pollutants by traditional wastewater treatment plants
  • Assessment of advanced tertiary treatment options to further remove micro-pollutants

2. Comparison of environmental impacts for different ways to handle sludge produced by waste water treatment

  • Incineration
  • Agricultural use
  • Digestion
  • Landfill

3. Indoor exposure in household setting, in a low impact house

Publications

  • Birkved M. and Hauschild, M.Z. SewageLCI 1.0 an inventory model capable of quantifying chemical emissions via the sewage system. Submitted
  • Ernstoff, A., Fantke P., Csiszar S., Henderson, A., Chung S., Jolliet, O. Completing the mass balance: a multi-pathway exposure model for chemicals in cosmetics. Submitted.
  • Golsteijn, L., Iqbal, M.S., Cassani, S., Hendriks, H.W.M., Kovarich, S., Papa, E., Rorije, E., Sahlin, U. & Huijbregts, M.A.J. 2014. Assessing Predictive Uncertainty. Environmental Toxicology and Chemistry, 33(2), 293-301. http://onlinelibrary.wiley.com/doi/10.1002/etc.2429/abstract
  • Golsteijn, L., Huizer D., Hauck, M., Van Zelm, R., Huijbregts, M.A.J. 2014. Including exposure variability in the life cycle impact assessment of indoor chemical emissions: The case of metal degreasing. Environment International 71: 36-45. http://www.sciencedirect.com/science/article/pii/S0160412014001780
  • Nijhof, C.O.P., Huijbregts, M.A.J., Golsteijn, L., Van Zelm, R. Spatial variability versus parameter uncertainty in freshwater fate and exposure factors of chemicals. Submitted to Chemosphere
  • Oldenkamp, R., Huijbregts, M.A.J., Ragas, A.M.J. The relevance of spatial differentiation in the probabilistic environmental prioritisation of pharmaceuticals. Submitted
  • Rosenbaum, R.K., Anton, A., Bengoa, X., Bjørn, A. Brain, R., Bulle, C., Cosme, N., Dijkman, T., Fantke, P., Felix, M., Geoghegan, T.S., Gottesbüren, B., Hammer, C., Humbert, S., Jolliet, O., Juraske, R., Lewis, F., Maxime, D., Nemecek, T., Payet, J., Räsänen, K., Roux, P., Schau, E.M., Sourisseau, S., van Zelm, R., von Streit, B. and Wallman, M. 2015. The Glasgow consensus on the delineation between pesticide emission inventory and impact assessment for LCA. The International Journal of Life Cycle Assessment. www.dx.doi.org/10.1007/s11367-015-0871-1
  • Rosenbaum, R.K., Meijer, A., Demou, E., Hellweg, S., Jolliet, O., Lam, N.L., Margni, M., McKone, T.E., 2015. Indoor air pollutant exposure for life cycle assessment: regional health impact factors for households. Environmental Science and Technology. doi:10.1021/acs.est.1025b00890
  • Westh, T., Hauschild, M.Z., Birkved, M., Joergensen, M.S., Rosenbaum, R.K. and Fantke, P. 2014. The USEtox story: a survey of model developer visionsand user requirements. International Journal of Life Cycle Assessment. http://dx.doi.org/10.1007/s11367-014-0829-8

TOX-TRAIN poster